Tests Use Epigenetics to Guess How Fast You're Aging

Updated: Jul 28, 2021

Before you proceed to the article, do not forget to listen to Episode 8 of Wellevate Life Podcast featuring Ryan Smith


● Ryan Smith is a mastermind in the field of Biochemistry and Medicals, who has aced USMLE Step 1.

● He started with his own pharmacy ‘Tailor Made Compounding’ which has become the 4th fastest growing company in healthcare and 21st fastest growing business in the US.

● Ryan’s company, TruDiagnostic is focusing on methylation array-based diagnostics for life extension and preventive healthcare.


FROM THE BEGINNING of time, humankind has searched for the secret to a long healthy life. Now science may have found an answer, in the form of molecular augury. The pattern of chemical chains that attach to the DNA in your cells—on-off switches known as epigenetic markers—can reveal how swiftly you are aging, and perhaps even how much longer you will live. While genetic testing might tell you where you came from, epigenetics promises a glimpse into the future. Now, a handful of companies like TruDiagnostics are offering commercial blood or saliva tests based on the science of epigenetics—a chance to find out how old you truly are.

Your epigenetic patterns change based on what you eat, how much you sleep or exercise, and what substances you are exposed to—and ultimately influence your risk of developing chronic conditions such as heart disease or diabetes. They do so by altering gene activity, like a complex set of controls that turn genes up or down, on or off. Epigenetics plays a role throughout life, from embryo development to aging, and some epigenetic changes accumulate as the years pass in a way that literally inscribes your age upon your body. That process is influenced by your environment and the things you do or don’t do. If you adopt a new exercise regimen or are exposed to pollutants, your epigenetic patterns may change for the better or worse.

To be brutally honest, there have been numerous attempts at finding the right ways to measure our lives and the risks that come in it. Telomere analysis and methylation clocks, transcriptomic-based, proteomic-based, and metabolomic-based predictors, and composite biomarkers are some of the tests tried already. Although an innovation can’t be criticised on the amount of tries

to attain excellence in testing. TruDiagnostic brings the world a new age test called the ‘Epigenetic Test’ which is the revolution of measuring health.

TruDiagnostic briefly tries to describe the simple differences in Biological and Chronological age. After all the test is designed to provide the information which lies in the grey area between the both. The chronological age is the number of years you have lived from birth. The biological age on the other hand, is the state and condition of your physical being. You may look or feel younger than expected, but this clock puts a number on it and tells you whether you really are aging more slowly than most other people. Having an independent health score is something more solid for anyone to consider changing their lifestyle routine.

To grasp on the concept of epigenetic test, it's crucial to know how stem cells play a vital role in the process of deducing the health. The stem cells telomere have the required information about an individual which also is used in the methylation clocks. The epigenetic test uses brain, telomere and glycan metrics as stem cells alone aren't enough to assure a particular result. Generally, though, these tests aren’t fortune tellers. You won’t learn exactly how long you have left to live. For one thing, random events—a serious infection, a car accident—play a huge role in lifespan.

The brain age, glycan age and telomere age together could become the foundations of diagnosing further coming health issues like dementia, osteoarthritis, cardiovascular diseases etc. The epigenetic tests have quite a few layers of work which involves different types of tests following specific purposes. You might catch their details better on the Wellevate Life PODCAST.

Habits acquired by us in these modern times like smoking, low diet, minimum movement and exercise can be the catalysts in aging. Stress of work, education, or the socioeconomic status can affect the epigenetic a lot. Alcohol in limits can be good for epigenetic rate. A fun fact that Ryan speaks of is that women age slower than men. African Americans tend to age slower than other ethnicities. The environmental factors directly impact on your aging as well.

To improve on your aging, you need to take into account a few things which shall be practiced every day. Ryan emphasises on Meditation and exercise primarily as they help in excessive circulation which is needed for the body and the mind both. A good sleep routine can optimally

bring the epigenetic rate to normal. Rushing into multiple of these tests won’t be a fruitful outcome, your telomeres start showing changes after around 5 years. That is when you must choose to take another test.

For now, our ability to turn back aging is somewhat limited to the familiar advice we already know so well: eat well, exercise, don’t smoke. But researchers are already using the epigenetic clock to test an anti-aging cocktail and diet. If a wellspring of youth exists, epigenetic tests may be the ultimate divining rod.